BDBM273176 (R)-N-benzyl-4-(7-ethyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)morpholine-3-carboxamide::US10065972, Example 645

SMILES CCc1cc(=O)n2nc(sc2n1)N1CCOC[C@@H]1C(=O)NCc1ccccc1

InChI Key InChIKey=ADZPNVJPUBLNTK-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273176   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273176((R)-N-benzyl-4-(7-ethyl-5-oxo-5H-[1,3,4]thiadiazol...)
Affinity DataIC50:  1.60E+3nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent