BDBM273182 (R)-N-benzyl-1-(6-methyl-8-oxo-8H-[1,3,4]thiadiazolo[3,2-a]thieno[2,3-d]pyrimidin-2-yl)pyrrolidine-2-carboxamide::US10065972, Example 656

SMILES Cc1cc2c(nc3sc(nn3c2=O)N2CCC[C@@H]2C(=O)NCc2ccccc2)s1

InChI Key InChIKey=UALRFLPQTZTYOL-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273182   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273182((R)-N-benzyl-1-(6-methyl-8-oxo-8H-[1,3,4]thiadiazo...)
Affinity DataIC50:  44nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent