BDBM273182 (R)-N-benzyl-1-(6-methyl-8-oxo-8H-[1,3,4]thiadiazolo[3,2-a]thieno[2,3-d]pyrimidin-2-yl)pyrrolidine-2-carboxamide::US10065972, Example 656
SMILES Cc1cc2c(nc3sc(nn3c2=O)N2CCC[C@@H]2C(=O)NCc2ccccc2)s1
InChI Key InChIKey=UALRFLPQTZTYOL-OAHLLOKOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273182
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 44nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair