BDBM273183 (1SR,2RS,5RS)-N-benzyl-3-(7-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)-3-azabicyclo[3.1.0]hexane-2-carboxamide::US10065972, Example 661

SMILES Cc1cc(=O)n2nc(sc2n1)N1C[C@@H]2C[C@@H]2[C@@H]1C(=O)NCc1ccccc1

InChI Key InChIKey=PXRBWPNANHRHQJ-OFQRWUPVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273183   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273183((1SR,2RS,5RS)-N-benzyl-3-(7-methyl-5-oxo-5H-[1,3,4...)
Affinity DataIC50:  3.90E+3nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent