BDBM273994 US10071079, Example 780::US10478424, Example 780

SMILES COCCNCC(=O)N1CCC(CC1)c1ccc2[nH]c(c(C(C)C)c2c1)-c1cc(OC)c2ncnn2c1

InChI Key InChIKey=SVZXXBGNPQPJKR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 273994   

TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM273994(US10071079, Example 780 | US10478424, Example 780)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM273994(US10071079, Example 780 | US10478424, Example 780)
Affinity DataIC50:  8nMT: 2°CAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 9(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM273994(US10071079, Example 780 | US10478424, Example 780)
Affinity DataIC50:  6.23E+3nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM273994(US10071079, Example 780 | US10478424, Example 780)
Affinity DataIC50:  0.400nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM273994(US10071079, Example 780 | US10478424, Example 780)
Affinity DataIC50:  8nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 9(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM273994(US10071079, Example 780 | US10478424, Example 780)
Affinity DataIC50:  6.23E+3nMT: 2°CAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent