BDBM27540 4-({3-[(4-acetyl-1,4-diazepan-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one::Homopiperazine analogue, 21

SMILES CC(=O)N1CCCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

InChI Key InChIKey=KIUVKKUPUFKEGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27540   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Pharmaceuticals

LigandPNGBDBM27540(4-({3-[(4-acetyl-1,4-diazepan-1-yl)carbonyl]-4-flu...)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed