BDBM275990 US10071974, Example 101::US10071974, Example 103::US10577336, Example 103

SMILES CC(C)(NC(=O)[C@@H]1CNCCO1)c1nc(C2CC2)c2c(F)cccn12

InChI Key InChIKey=FPHMOSOQACAAJX-ZDUSSCGKSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 275990   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275990(US10071974, Example 101 | US10071974, Example 103 ...)
Affinity DataEC50:  6.5nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275990(US10071974, Example 101 | US10071974, Example 103 ...)
Affinity DataEC50:  60.7nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275990(US10071974, Example 101 | US10071974, Example 103 ...)
Affinity DataEC50:  6.5nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM275990(US10071974, Example 101 | US10071974, Example 103 ...)
Affinity DataEC50:  60.7nMpH: 7.4 T: 2°CAssay Description:Compounds are dissolved and diluted in DMSO. The final test solution contains 1% DMSO. The cAMP standard (Lance cAMP 384 Kit; PerkinElmer, Cat# AD026...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent