BDBM276054 4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyridin-4-yl]-1H-triazole-5-carbonitrile::US10071984, Example 16::US9896436, Example 16

SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1

InChI Key InChIKey=SZQNWLSVYUSLQI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276054   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276054(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Affinity DataIC50: <100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276054(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Affinity DataIC50:  300nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276054(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276054(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent