BDBM276058 2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-(5-fluoro-1H-triazol-4-yl)pyridine::US10071984, Example 20::US10174003, Example 20::US9896436, Example 20

SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2cccc(Cl)c2Cl)cn1

InChI Key InChIKey=BMWOUCCUJBHODC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276058   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276058(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50: <100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276058(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50:  300nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276058(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM276058(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent