BDBM277314 1'-benzyl-2,4-dihydro-1H-spiro[isoquinoline-3,4'-piperidin]-1-one::US10072008, Example 2
SMILES O=C1NC2(CCN(Cc3ccccc3)CC2)Cc2ccccc12
InChI Key InChIKey=QXZPUHQWBMEROC-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 277314
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals
US Patent
Esteve Pharmaceuticals
US Patent
Affinity DataKi: <100nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair