BDBM2776 Alkenyldiarylmethane (ADAM) 18a::Alkenyldiarylmethanes (ADAM) 18a::Methyl 3,3-Di(methoxycarbonyl)-5,5-bis(trifluoromethyl)-4,4-dimethoxy-6,6-diphenyl-5-hexenoate::methyl 2-methoxy-5-{6-methoxy-1-[4-methoxy-3-(methoxycarbonyl)-5-(trifluoromethyl)phenyl]-6-oxohex-1-en-1-yl}-3-(trifluoromethyl)benzoate

SMILES [#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]\[#6]=[#6](/c1cc(-[#6](=O)-[#8]-[#6])c(-[#8]-[#6])c(c1)C(F)(F)F)-c1cc(-[#6](=O)-[#8]-[#6])c(-[#8]-[#6])c(c1)C(F)(F)F

InChI Key InChIKey=DFTVXGMFZBXHRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2776   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2776(Alkenyldiarylmethane (ADAM) 18a | Alkenyldiarylmet...)
Affinity DataIC50: >2.00E+5nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
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