BDBM277692 N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-5-(2-(2-((5-oxo-2,5-dihydroisoxazol-3-yl)methoxy)ethoxy)ethoxy)phenyl)amino)pyridin-4-yl)oxy)naphthalen-1-yl)ureido)phenyl)-methanesulfonamide::US10072034, Example 18

SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCc2cc(=O)o[nH]2)c1

InChI Key InChIKey=CTLNCXSFLPZJFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277692   

TargetInterleukin-8(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM277692(N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-...)
Affinity DataIC50:  29.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent