BDBM27878 13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-triene-5-carboxamide::MMP Inhibitor, 7::hexahydrobenzothienopyrimidine, 2
SMILES NC(=O)CC1CCCc2sc3nc([nH]c(=O)c3c12)C(=O)NCc1ccc2OCC(=O)Nc2c1
InChI Key InChIKey=ITADELAVAWJACR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 25 hits for monomerid = 27878
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMpH: 6.0 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: <25nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: <25nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP14 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...More data for this Ligand-Target Pair