BDBM278827 2-(1,4-diazepan-1-yl)- N-[1-methyl-3- (trifluoromethyl)-1H- pyrazol-4-yl] thieno[2,3-b] pyrazine-7- carboxamide::US10040802, Example 6

SMILES Cn1cc(NC(=O)c2csc3ncc(nc23)N2CCCNCC2)c(n1)C(F)(F)F

InChI Key InChIKey=OLTBSNVUBBDTIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 278827   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM278827(2-(1,4-diazepan-1-yl)- N-[1-methyl-3- (trifluorome...)
Affinity DataIC50:  17nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent