BDBM278841 N-(3-bromo-1-methyl- 1H-pyrazol-4-yl)-2- [(1S,4S)- or (1R,4R)- 2,5-diazabicyclo[2.2.2] oct-2-yl]thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 20
SMILES OC(=O)C(F)(F)F.Cn1cc(NC(=O)c2csc3ncc(nc23)N2C[C@H]3CC[C@@H]2CN3)c(Br)n1
InChI Key InChIKey=VFSFIEOIWVINSK-DHTOPLTISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278841
Affinity DataIC50: 19nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair