BDBM278858 2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-(3-cyano-1- methyl-1H-pyrazol- 4-yl)thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 37
SMILES OC(=O)C(F)(F)F.Cn1cc(NC(=O)c2csc3ncc(N[C@@H]4CCCC[C@@H]4N)nc23)c(n1)C#N
InChI Key InChIKey=ALQUGCIGAFDXKI-ZVWHLABXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278858
Affinity DataIC50: 0.400nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair