BDBM278860 2-{[(1R,2R)-2-amino- 3,3-difluorocyclohexyl] amino}-N-[3- (difluoromethyl)-1- methyl-1H-pyrazol- 4-yl]thieno[2,3-b] pyrazine-7- carboxamide::US10040802, Example 39
SMILES Cn1cc(NC(=O)c2csc3ncc(N[C@@H]4CCCC(F)(F)[C@@H]4N)nc23)c(n1)C(F)F
InChI Key InChIKey=FSPFOJZKCRINCY-YMTOWFKASA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278860
Affinity DataIC50: 32nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair