BDBM278934 4-{8-amino-3- [(7S,9aR)-7-methyl-2- (1-methylethyl)-4- oxooctahydro-2H- pyrido[1,2-a]pyrazin-7- yl]imidazo[1,5-a] pyrazin-1-yl}-3- ethoxy-N-[1-methyl-5- (trifluoromethyl)- 1H-pyrazol-3- yl]benzamide::US10040805, Example 4

SMILES CCOc1cc(ccc1-c1nc(n2ccnc(N)c12)[C@@]1(C)CC[C@@H]2CN(CC(=O)N2C1)C(C)C)C(=O)Nc1cc(n(C)n1)C(F)(F)F

InChI Key InChIKey=NWIWNHWXFQJQED-QJWGWKRISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 278934   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM278934(4-{8-amino-3- [(7S,9aR)-7-methyl-2- (1-methylethyl...)
Affinity DataIC50:  2.5nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent