BDBM278935 4-[8-amino-3-(2,7- diethyl-1- oxooctahydro-1H- pyrido[1,2-c] pyrimidin-7- yl)imidazo[1,5-a] pyrazin-1-yl]-3- ethoxy-N-[4- (trifluoromethyl) pyridin-2-yl] benzamide::US10040805, Example 5::US10040805, Example 6

SMILES CCOc1cc(ccc1-c1nc(n2ccnc(N)c12)C1(CC)CCC2CCN(CC)C(=O)N2C1)C(=O)Nc1cc(ccn1)C(F)(F)F

InChI Key InChIKey=XCRZCUHVZXRYBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 278935   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM278935(4-[8-amino-3-(2,7- diethyl-1- oxooctahydro-1H- pyr...)
Affinity DataIC50:  215nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM278935(4-[8-amino-3-(2,7- diethyl-1- oxooctahydro-1H- pyr...)
Affinity DataIC50:  1.00E+3nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent