BDBM278942 4-[8-amino-3-(2,7- dimethyl-1- oxooctahydro-1H- pyrido[1,2-c] pyrimidin-7- yl)imidazo[1,5-a] pyrazin-1-yl}-3- ethoxy-N-[4- (trifluoromethyl) pyridin-2-yl] benzamide::US10040805, Example 12::US10040805, Example 13
SMILES CCOc1cc(ccc1-c1nc(n2ccnc(N)c12)C1(C)CCC2CCN(C)C(=O)N2C1)C(=O)Nc1cc(ccn1)C(F)(F)F
InChI Key InChIKey=IPKWFJWKRLRNPZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 278942
Affinity DataIC50: 10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 411nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair