BDBM278946 4-{8-amino-3- [(7R,9aS)-7-methyl-2- (1-methylethyl)-4- oxooctahydro-2H- pyrido[1,2-a]pyrazin- 7-yl]imidazo[1,5-a] pyrazin-1-yl}-2- chloro-5-ethoxy-N-[1- methyl-5- (trifluoromethyl)-1H- pyrazol-3-yl] benzamide::US10040805, Example 16
SMILES CCOc1cc(C(=O)Nc2cc(n(C)n2)C(F)(F)F)c(Cl)cc1-c1nc(n2ccnc(N)c12)[C@]1(C)CC[C@H]2CN(CC(=O)N2C1)C(C)C
InChI Key InChIKey=LJXWQAPQSXWRSM-FZEVHQGJSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278946
Affinity DataIC50: 3.41nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair