BDBM279501 1-isopropyl-4-(6-(pyridin-4-yl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one::US10035777, Example 51

SMILES CC(C)N1CC(CC1=O)C(=O)Nc1ccc(cc1N)-c1ccncc1

InChI Key InChIKey=FWINUCOMTHZFBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279501   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM279501(1-isopropyl-4-(6-(pyridin-4-yl)-1H-benzo[d]imidazo...)
Affinity DataIC50:  783nMpH: 7.4 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent