BDBM279687 US10035797, Compound 25::US10428068, Compound 25::US10844056, Compound 25::US11560377, Compound 25::US9630965, Compound 25

SMILES Nc1nccc2n(CCCCC#C)c(Sc3cc4OCOc4cc3I)nc12

InChI Key InChIKey=PPDMTNVDBKBFSR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 279687   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Curis

US Patent
LigandPNGBDBM279687(US10035797, Compound 25 | US10428068, Compound 25 ...)
Affinity DataIC50:  550nMpH: 7.3Assay Description:A fluorescein isothiocyanate (FITC) labeled GM was purchase from InvivoGen (ant-fgl-1). The interaction between HSP90 and labeled GM forms the basis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Curis

US Patent
LigandPNGBDBM279687(US10035797, Compound 25 | US10428068, Compound 25 ...)
Affinity DataIC50:  550nMAssay Description:A fluorescein isothiocyanate (FITC) labeled GM was purchase from InvivoGen (ant-fgl-1). The interaction between HSP90 and labeled GM forms the basis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Curis

US Patent
LigandPNGBDBM279687(US10035797, Compound 25 | US10428068, Compound 25 ...)
Affinity DataIC50:  550nMAssay Description:A fluorescein isothiocyanate (FITC) labeled GM was purchase from InvivoGen (ant-fgl-1). The interaction between HSP90 and labeled GM forms the basis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Curis

US Patent
LigandPNGBDBM279687(US10035797, Compound 25 | US10428068, Compound 25 ...)
Affinity DataIC50:  550nMAssay Description:A fluorescein isothiocyanate (FITC) labeled GM was purchase from InvivoGen (ant-fgl-1). The interaction between HSP90 and labeled GM forms the basis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Curis

US Patent
LigandPNGBDBM279687(US10035797, Compound 25 | US10428068, Compound 25 ...)
Affinity DataIC50:  550nMAssay Description:HSP90: A fluorescein isothiocyanate (FITC) labeled GM was purchase from InvivoGen (ant-fgl-1). The interaction between HSP90 and labeled GM forms the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent