BDBM28044 7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-carboxamide::thieno[2,3-c]pyridine, 10b
SMILES NC(=O)c1cc2c(cnc(N)c2s1)-c1cccc(c1)-c1ccccc1
InChI Key InChIKey=FIFCMZNMAHBCDZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 28044
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMpH: 7.5 T: 2°CAssay Description:The ERK HTRF assays were carried out using biotin-MBP protein as a substrate. The reaction was carried out in black 96 half-well plates. At designate...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataIC50: 1.30E+4nMpH: 7.5 T: 2°CAssay Description:MEK1 cascade HTRF assays were carried out using inactive Erk2 as a downstream kinase with biotin-MBP protein as the final substrate. The reaction was...More data for this Ligand-Target Pair