BDBM28044 7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-carboxamide::thieno[2,3-c]pyridine, 10b

SMILES NC(=O)c1cc2c(cnc(N)c2s1)-c1cccc(c1)-c1ccccc1

InChI Key InChIKey=FIFCMZNMAHBCDZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28044   

TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM28044(7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-...)
Affinity DataIC50:  160nMpH: 7.5 T: 2°CAssay Description:The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM28044(7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-...)
Affinity DataIC50:  4.30E+3nMpH: 7.5 T: 2°CAssay Description:The ERK HTRF assays were carried out using biotin-MBP protein as a substrate. The reaction was carried out in black 96 half-well plates. At designate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM28044(7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-...)
Affinity DataIC50:  1.30E+4nMpH: 7.5 T: 2°CAssay Description:MEK1 cascade HTRF assays were carried out using inactive Erk2 as a downstream kinase with biotin-MBP protein as the final substrate. The reaction was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed