BDBM280907 (S)-3-(2-{4-amino- 2-[6-chloro-1-(2,6- difluorobenzyl)-1H- indazol-3-yl]-5- methyl-6-oxo- 6,7-dihydro-5H- pyrrolo[2,3-d] pyrimidin-5-yl}- 1,3-thiazol-4-yl)- 2,2-dimethyl- propanoic acid::US10030027, Example 183A::US10428076, Example 183A
SMILES CC(C)(Cc1csc(n1)[C@]1(C)C(=O)Nc2nc(nc(N)c12)-c1nn(Cc2c(F)cccc2F)c2cc(Cl)ccc12)C(O)=O
InChI Key InChIKey=NGYGMLWRRYQUAW-LJAQVGFWSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 280907
Affinity DataKi: 0.0760nMpH: 7.4Assay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair