BDBM28158 5-(1H-1,3-benzodiazol-1-yl)-3-[(3-methylphenyl)methoxy]thiophene-2-carboxamide::benzimidazole thiophene analogue, 8

SMILES Cc1cccc(COc2cc(sc2C(N)=O)-n2cnc3ccccc23)c1

InChI Key InChIKey=UGQFNSQKIGSKJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28158   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Gsk

LigandPNGBDBM28158(5-(1H-1,3-benzodiazol-1-yl)-3-[(3-methylphenyl)met...)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed