BDBM28237 2-(7-{5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-3-yl}-8-hydroxy-1,6-naphthyridin-5-yl)-1,2-thiazinane-1,1-dione::C5-sultam substituted naphthyridine, 26

SMILES Oc1c(nc(N2CCCCS2(=O)=O)c2cccnc12)-c1noc(Cc2ccc(F)cc2)n1

InChI Key InChIKey=GHCVXZBYNANXFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28237   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28237(2-(7-{5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-3...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed