BDBM282570 (3R)-5-(3-chloro-5-fluoro-phenoxy)-3-hydroxy-1,1- dioxo-2,3-dihydrobenzothiophene-4-carbonitrile::US9884843, Compound 2

SMILES O[C@H]1CS(=O)(=O)c2ccc(Oc3cc(F)cc(Cl)c3)c(C#N)c12

InChI Key InChIKey=IHQLDRVSYYRWIM-LBPRGKRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282570   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM282570((3R)-5-(3-chloro-5-fluoro-phenoxy)-3-hydroxy-1,1- ...)
Affinity DataIC50:  47nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent