BDBM282702 (R)-3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy- 1,1-dioxido-2,3-dihydrobenzo[b]thiophen-5-yl)oxy)- 5-methylbenzonitrile::US9884843, Compound 46

SMILES Cc1cc(Oc2ccc3c([C@@H](O)C(F)(F)S3(=O)=O)c2C(F)F)cc(c1)C#N

InChI Key InChIKey=OMOWWWUJUPOYGO-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282702   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM282702((R)-3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent