BDBM282741 (R)-3-((4-chloro-2,2-difluoro-3-hydroxy-1,1-dioxido- 2,3-dihydrobenzo[b]thiophen-5-yl)oxy)-5- fluorobenzonitrile::US9884843, Compound 85

SMILES O[C@@H]1c2c(ccc(Oc3cc(F)cc(c3)C#N)c2Cl)S(=O)(=O)C1(F)F

InChI Key InChIKey=ZDPNZKNOAZAZEZ-CQSZACIVSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 282741   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM282741((R)-3-((4-chloro-2,2-difluoro-3-hydroxy-1,1-dioxid...)
Affinity DataEC50:  77nMAssay Description:About 7500 of 786-O cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM282741((R)-3-((4-chloro-2,2-difluoro-3-hydroxy-1,1-dioxid...)
Affinity DataIC50:  11nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent