BDBM282746 (R)-4-(Difluoromethyl)-5-(3,4-difluorophenoxy)-2,2- difluoro-3-hydroxy-2,3-dihydrobenzo[b]thiophene 1,1-dioxide::US9884843, Compound 90

SMILES O[C@@H]1c2c(ccc(Oc3ccc(F)c(F)c3)c2C(F)F)S(=O)(=O)C1(F)F

InChI Key InChIKey=POXQPQFXCJRBLG-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282746   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM282746((R)-4-(Difluoromethyl)-5-(3,4-difluorophenoxy)-2,2...)
Affinity DataIC50:  24nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent