BindingDB BDBM283231 2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-phenyl)-1-methyl- 6-oxo-1,6-dihydro-pyrimidine-5- carbonitrile::US10023543, Example 121::US10023543, Example 19::US10207999, Example 121::US10328077, Example 19::US10548896, Example 121::US10849898, Example 121::US10960005, Example 121::US11084793, Example 121::US9573930, Example 121::US9771329, Example 121::US9776974, Example 121

BDBM283231 2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-phenyl)-1-methyl- 6-oxo-1,6-dihydro-pyrimidine-5- carbonitrile::US10023543, Example 121::US10023543, Example 19::US10207999, Example 121::US10328077, Example 19::US10548896, Example 121::US10849898, Example 121::US10960005, Example 121::US11084793, Example 121::US9573930, Example 121::US9771329, Example 121::US9776974, Example 121

SMILES Cn1c(nc(-c2ccc(C#N)c(F)c2)c(C#N)c1=O)N1CCC(N)CC1

InChI Key InChIKey=FVPWXEWCBKXACC-UHFFFAOYSA-N

Data 22 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 283231

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:The enzymatic assay of LSD-1 activity is based on Tnne Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMAssay Description:The enzymatic assay of LSD-1 activity is based on Tnne Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Lysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent

PNG

BDBM283231(2-(4-amino-piperidin-1-yl)-4-(4- cyano-3-fluoro-ph...)

IC50: 550nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent