BDBM283249 4-{2-(4-amino-piperidin-1-yl)-1- methyl-6-oxo-5-[1-(2,2,2-trifluoro- ethyl)-1H-pyrazol-4-yl]-1,6- dihydro-pyrimidin-4-yl}-2-fluoro- benzonitrile::US10023543, Example 34::US10207999, Example 34::US10328077, Example 34::US10548896, Example 34::US10849898, Example 34::US10960005, Example 34::US11084793, Example 34::US9573930, Example 34::US9771329, Example 34::US9776974, Example 34
SMILES Cn1c(nc(-c2ccc(C#N)c(F)c2)c(-c2cnn(CC(F)(F)F)c2)c1=O)N1CCC(N)CC1
InChI Key InChIKey=BDWAHZDJZINOHA-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 283249
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair