BDBM283437 N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((3-chloro-8-fluoroquinolin-6- yl)methyl)isonicotinamide::US10023557, Example 89::US10266515, Example 89::US10308637, Example 89::US11021463, Example 89::US9611252, Example 89

SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2cc(F)c3ncc(Cl)cc3c2)c1

InChI Key InChIKey=NJQUWZKNWYIFOW-UHFFFAOYSA-N

Data  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283437   

TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283437(N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...)
Affinity DataIC50: <100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent