BDBM283516 4'-(3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazin-7- yl)-3'-fluoro-N-[(1R)-2-hydroxy-1- methylethyl]biphenyl-2-sulfonamide::US9745328, Compound 390::US9884878, Compound 390
SMILES C[C@H](CO)NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc2NCCOc2c1
InChI Key InChIKey=DSODKTGYNFIXOL-CQSZACIVSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 283516
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataKi: <0.100nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...More data for this Ligand-Target Pair