BDBM284077 US10023570, Example 87
SMILES C[N]1=CC(=CN1)c1cc(-c2ccc(nc2)N2CCN(CC2)S(=O)(=O)CC2CC2)c2c(cnn2c1)C#N
InChI Key InChIKey=JKFRZJXSULRTDW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 284077
TargetProto-oncogene tyrosine-protein kinase receptor Ret [658-1114](Homo sapiens (Human))
Array Biopharma
US Patent
Array Biopharma
US Patent
Affinity DataIC50: 5.30nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF® KinEASE -TK ...More data for this Ligand-Target Pair