BDBM284767 US10023575, Example 58::US10023575, Example 92a::US10023575, Example 92b::US10023575, Example 93a::US10023575, Example 93b::US10479794, Example 93b::US10875867, Example 58::US11691977, Example 58
SMILES Cc1cnc2c(cnn2c1)C(=O)NC1(COCC1(C)O)c1ccc(cc1F)C(F)(F)F
InChI Key InChIKey=TVEAFXBHWJGOGR-UHFFFAOYSA-N
Data 24 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 284767
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 14nMAssay Description:The inhibition of PDE 2A or 10 enzyme activity was assessed using IMAP-Phosphodiesterase-cAMP fluorescence labeled substrate (Molecular Devices, Orde...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of PDE 2A or 10 enzyme activity was assessed using IMAP-Phosphodiesterase-cAMP fluorescence labeled substrate (Molecular Devices, Orde...More data for this Ligand-Target Pair