BDBM28484 (2S)-2-({11-[(4-fluorophenoxycarbonyl)amino]-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene-5-}sulfonamido)-3-methylbutanoic acid::dibenzofuran (DBF) scaffold, (S)-29

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1cc(NC(=O)Oc3ccc(F)cc3)ccc21)C(O)=O

InChI Key InChIKey=RJKVRZJNTANTQB-QFIPXVFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28484   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28484((2S)-2-({11-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)
Affinity DataIC50:  361nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28484((2S)-2-({11-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed