BDBM28486 (2R)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(13),2,4,6,9,11-hexaene-4-sulfonamido}butanoic acid::dibenzofuran (DBF) scaffold, (R)-2a

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc2oc3ccccc3c2c1)C(O)=O

InChI Key InChIKey=YGNCGRVNRKDKCS-MRXNPFEDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 28486   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28486((2R)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  38nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28486((2R)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28486((2R)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28486((2R)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  2.50E+3nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed