BDBM284986 US10023592, Example 31::US10941160, Example 31::tert-butyl N-methyl-N-[3-(2-methyl-1- oxoisoquinolin-4-yl)phenyl]carbamate

SMILES CN(C(=O)OC(C)(C)C)c1cccc(c1)-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=ZVRRQTRSCAGPCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 284986   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM284986(US10023592, Example 31 | US10941160, Example 31 | ...)
Affinity DataIC50:  2.75E+3nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM284986(US10023592, Example 31 | US10941160, Example 31 | ...)
Affinity DataIC50:  2.75E+3nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent