BDBM285033 N-[3-(2,6-dimethyl-1-oxoisoquinolin-4-yl) phenyl]methanesulfonamide::US10023592, Example 78
SMILES Cc1ccc2c(c1)c(cn(C)c2=O)-c1cccc(NS(C)(=O)=O)c1
InChI Key InChIKey=YLQFVVLUOPIKAX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 285033
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair