BDBM285474 4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-3-ylcarbamoyl)-2,3-dihydrospiro[chromene-4,1′-cyclopropan]-2′-yl]carbonyl}amino)phenyl]butanoic acid::US10077247, Example 2-37

SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)Nc1ccon1)C#N

InChI Key InChIKey=VGFMUBUZWSBMFB-DCFHFQCYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285474   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285474(4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-3-ylc...)
Affinity DataIC50:  3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent