BDBM285644 4,6-Dimethyl-5-[2-methyl-4-([1,2]thiazolo[4,5-c]pyridin-4-yloxy)phenyl]pyridazin-3(2H)-::US10077272, Example 10::US9868744, 10

SMILES Cc1cc(Oc2nccc3sncc23)ccc1-c1c(C)n[nH]c(=O)c1C

InChI Key InChIKey=DJKDVAOFTSDURD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285644   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285644(4,6-Dimethyl-5-[2-methyl-4-([1,2]thiazolo[4,5-c]py...)
Affinity DataKi:  32.7nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285644(4,6-Dimethyl-5-[2-methyl-4-([1,2]thiazolo[4,5-c]py...)
Affinity DataKi:  32.7nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent