BDBM285647 5-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]-4,6-dimethylpyridazin-3(2H)-one::US10077272, Example 13::US9868744, 13

SMILES Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2ncnc3occc23)cc1

InChI Key InChIKey=VABBXBQQRLJXBV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285647   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285647(5-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]-4,6-dim...)
Affinity DataKi:  70.3nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285647(5-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]-4,6-dim...)
Affinity DataKi:  70.3nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent