BDBM285657 1,5-diethyl-6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]pyrimidine-2,4(1H,3H)-dione::US10077272, Example 23::US9868744, 23

SMILES CCc1c(-c2ccc(Oc3ncnc4occc34)cc2)n(CC)c(=O)[nH]c1=O

InChI Key InChIKey=DJMXGDHFBXNKSO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285657   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285657(1,5-diethyl-6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phe...)
Affinity DataKi:  309nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285657(1,5-diethyl-6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phe...)
Affinity DataKi:  309nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent