BDBM28580 1-sulfonylindazole, 7b::N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]piperidine-3-carboxamide

SMILES O=C(Nc1ccc2cnn(c2c1)S(=O)(=O)c1cccc2ccccc12)C1CCCNC1

InChI Key InChIKey=NDTCTCKVFXXKQH-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 28580   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  1.30nM ΔG°:  -12.0kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  174nM ΔG°:  -9.12kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  1.80E+3nM ΔG°:  -7.75kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi: >2.00E+3nM ΔG°: >-7.69kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi: >2.00E+3nM ΔG°: >-7.69kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  5.60E+3nM ΔG°:  -7.09kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  5.80E+3nM ΔG°:  -7.07kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed