BDBM286302 5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyquinolin-3-yl)- 1H-pyrazole-4-carboxamide MS (ESI) (M + H)+ = 372.5::US9518026, Example 95::US9956214, Compound 1629

SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(CO)CO)c(N)c1C(N)=O

InChI Key InChIKey=FCDBILPMWMBUOR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 286302   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286302(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)
Affinity DataIC50:  11nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286302(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)
Affinity DataIC50:  52nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286302(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)
Affinity DataIC50:  120nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM286302(5-amino-1-(1,3-dihydroxypropan- 2-yl)-3-(7-ethoxyq...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent