BDBM28661 2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic acid::CHEMBL38943::GW 501516::GW-501516::GW1516::GW501516
SMILES Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F
InChI Key InChIKey=YDBLKRPLXZNVNB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 28661
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Sahmyook University
Curated by ChEMBL
Sahmyook University
Curated by ChEMBL
Affinity DataIC50: 5nM EC50: 3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]GW 2433 from human PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Sahmyook University
Curated by ChEMBL
Sahmyook University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]GW 2433 from human PPARdelta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Displacement of [3H]GW 2433 from human PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Sahmyook University
Curated by ChEMBL
Sahmyook University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity for human PPAR delta receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Sahmyook University
Curated by ChEMBL
Sahmyook University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 463nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPAMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Sahmyook University
Curated by ChEMBL
Sahmyook University
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human PPARdelta ligand binding domain-mediated transcriptional activity in CV1 cells by Gal4 chimera reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Sahmyook University
Curated by ChEMBL
Sahmyook University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair