BDBM287089 N-(1-(2-(Piperidin-1- yl)ethyl)-1H-pyrazolo[3,4- d]pyrimidin-4-yl)pivalamide maleate::US9567338, 5
SMILES CC(C)(C)C(=O)Nc1ncnc2n(CCN3CCCCC3)ncc12
InChI Key InChIKey=ZRBAZCUVMYLCMU-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 287089
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratorios Del Dr. Esteve
US Patent
Laboratorios Del Dr. Esteve
US Patent
Affinity DataKi: 50.6nMpH: 7.4Assay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma-1 receptor expressed in HEK293 cell membranes after 120 mins by HTS assayMore data for this Ligand-Target Pair