BDBM287591 US10420768, Compound C-18::US9567341, Compound C-18
SMILES Fc1cc(cnc1C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12)C(F)(F)F
InChI Key InChIKey=XEMWYEQYFGPCEW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 287591
Affinity DataIC50: 84nMpH: 7.35Assay Description:The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37° C. in a humidified CO2 incubator in the grow...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+7nMpH: 7.4Assay Description:Inhibitory activities of test compounds on 5 major isoforms of CYP P450 were evaluated by using pooled human liver microsome (HLM, purchased from BD ...More data for this Ligand-Target Pair