BDBM287654 US10085984, Example 32::US11040034, Ex. No. 32
SMILES Fc1cc2nc(-c3cnnc(NCC(F)(F)F)c3)n(C3CC3)c2cc1F
InChI Key InChIKey=ALHYMIQYVWZAGO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 287654
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Viamet Pharmaceuticals (Bermuda)
US Patent
Viamet Pharmaceuticals (Bermuda)
US Patent
Affinity DataIC50: <100nMAssay Description:V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Viamet Pharmaceuticals (Bermuda)
US Patent
Viamet Pharmaceuticals (Bermuda)
US Patent
Affinity DataIC50: 50nMAssay Description:Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...More data for this Ligand-Target Pair